Computational Flu Vaccine

Methods

The Reverse Vaccinology Approach

FutureFlu is utilizing bioinformatics tools and custom developed software to calculate the candidate seasonal vaccine for the upcoming flu season. For two years in a row, the computed vaccines have been a perfect match with those recommended later by the World Health Organization (WHO) and Centers for Disease Control (CDC).

Flu Vaccine 101

Analytics

FutureFlu has created a Fourier-enhanced Phylogeny/Antigenicity Predictive Model (F^P/A-PM) to calculate the seasonal flu vaccine. The mathematical model analyzes the historical influenza data using reverse vaccinology. Reverse vaccinology is the science of studying the dynamic patterns in the genomic data to select antigenic targets and to design vaccines. It blends computational biology with the conventional lab-based assays.

Is Reverse Vaccinology the Future?

What's New

2018-12-12. FutureFlu recommends A/Michigan/45/2015 (A/H1N1pdm) and A/Netherlands/10160/2018 (A/H3N2) vaccine for the 2019-20 flu season.

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